Where is csf produces
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However, the arachnoid villi act as "one way valves" In other words, the CSF acts to cushion a blow to the head and lessen the impact. Buoyancy : because the brain is immersed in fluid, the net weight of the brain is reduced from about 1, gm to about 50 gm.
Therefore, pressure at the base of the brain is reduced. Excretion of waste products : the one-way flow from the CSF to the blood takes potentially harmful metabolites, drugs and other substances away from the brain. Endocrine medium for the brain : the CSF serves to transport hormones to other areas of the brain. Hormones released into the CSF can be carried to remote sites of the brain where they may act.
Image adapted from Biodidac. Under some pathological conditions, CSF builds up within the ventricles. CSF flows from the lateral ventricles through two narrow passageways into the third ventricle. From the third ventricle, it flows down another long passageway known as the aqueduct of Sylvius into the fourth ventricle. From the fourth ventricle, it passes through three small openings called foramina and into the subarachnoid space surrounding the brain and the spinal cord.
If the flow of CSF at any of these points is blocked, hydrocephalus can develop. This is often referred to as non-communicating hydrocephalus. It has traditionally been thought that CSF is absorbed through tiny, specialized cell clusters called arachnoid villi near the top and midline of the brain. The CSF then passes through the arachnoid villi into the superior sagittal sinus, a large vein, and is absorbed into the bloodstream.
Once in the bloodstream, it is carried away and filtered by the kidneys and liver in the same way as other bodily fluids. However, more recent research has shown that CSF is also absorbed through other pathways as well.
When CSF absorption is blocked or reduced, hydrocephalus can develop. This is often referred to as communicating hydrocephalus because there is no obvious blockage within the ventricular system. Information you can trust! This article has been reviewed by members of our Medical Advisory Board and other professionals in the field.
Cerebrospinal Fluid Dynamics Relevant to Hydrocephalus. About Hydrocephalus. Hydrocephalus in Pregnancy. Hydrocephalus in Infants and Children.
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